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- Description:
- Background. Common cold viruses create significant health and financial burdens, and understanding key loci of transmission would help focus control strategies. This study (1) examines factors that influence when individuals transition from a negative to positive test (acquisition) or a positive to negative test (loss) of rhinovirus (HRV) and other respiratory tract viruses in 26 households followed weekly for one year, (2) investigates evidence for intrahousehold and interhousehold transmission and the characteristics of individuals implicated in transmission, and (3) builds data-based simulation models to identify factors that most strongly affect patterns of prevalence. Methods. We detected HRV, coronavirus, paramyxovirus, influenza and bocavirus with the FilmArray polymerase chain reaction (PCR) platform (BioFire Diagnostics, LLC). We used logistic regression to find covariates affecting acquisition or loss of HRV including demographic characteristics of individuals, their household, their current infection status, and prevalence within their household and across the population. We apply generalized linear mixed models to test robustness of results. Results. Acquisition of HRV was less probable in older individuals and those infected with a coronavirus, and higher with a higher proportion of other household members infected. Loss of HRV is reduced with a higher proportion of other household members infected. Within households, only children and symptomatic individuals show evidence for transmission, while between households only a higher number of infected older children (ages 5-19) increases the probability of acquisition. Coronaviruses, paramyxoviruses and bocavirus also show evidence of intrahousehold transmission. Simulations show that age-dependent susceptibility and transmission have the largest effects on mean HRV prevalence. Conclusions. Children are most likely to acquire and most likely to transmit HRV both within and between households, with infectiousness concentrated in symptomatic children. Simulations predict that the spread of HRV and other respiratory tract viruses can be reduced but not eliminated by practices within the home.
- Creator:
- Adler, Frederick R.
- Contributor:
- Ampofo, Krow, Pavia, Andrew, and Byington, Carrie L.
- Owner:
- BRIAN MCBRIDE
- Based Near Label Tesim:
- Salt Lake City, Utah, United States
- Language:
- English
- Date Uploaded:
- 07/10/2019
- Date Modified:
- 12/09/2021
- Date Created:
- August 2009 - August 2010
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S5XG9P97
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- Description:
- This dataset accounts for all jobs undertaken by the Société Le Roy Bouillon, a funerary monuments company in Paris, from 1890 to 1902. The first sheet, “Activity Data” accounts for each job and the fee charged to the client for that job. It also categories each job as either a new cemetery construction, maintenance to existing cemetery structures, or other jobs unrelated to cemetery construction. The second sheet, “Outside Paris,” summarizes the annual activity, recording the number of projects undertaken within Paris versus outside of the city, new constructions versus maintenance work, and revenue coming in from each type of job. The original records are currently housed in a private collection in Paris and were manually transcribed by the author.
- Keyword:
- Paris, France, funerary monuments, nineteenth centruy, cemeteries, and business history
- Subject:
- funerary structures, cemeteries, and nineteenth century (dates CE)
- Creator:
- Kaylee P. Alexander
- Owner:
- Kaylee Alexander
- Based Near Label Tesim:
- Paris, Île-de-France, France
- Language:
- English
- Date Uploaded:
- 02/09/2023
- Date Modified:
- 11/30/2023
- Date Created:
- 2020-01-01 to 2020-01-31
- License:
- CC BY NC - Allows others to use and share your data non-commercially and with attribution.
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S50d-t4sn-67e3
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- Description:
- Weather-related research often requires synthesizing vast amounts of data that need archival solutions that are both economical and viable during and past the lifetime of the project. Public cloud computing services (e.g., from Amazon, Microsoft, or Google) or private clouds managed by research institutions are providing object data storage systems appropriate for long-term archives of such large geophysical data sets. , Current Status: Our research group no longer needs to maintain archives of High Resolution Rapid Refresh (HRRR) model output at the University of Utah since complete publicly-accessible archives of HRRR model output are now available from the Google Cloud Platform and Amazon Web Services (AWS) as part of the NOAA Open Data Program. Google and AWS store the HRRR model output in GRIB2 format, a file type that efficiently stores hundreds of two-dimensional variable fields for a single valid time. Despite the highly compressible nature of GRIB2 files, they are often on the order of several hundred MB each, making high-volume input/output applications challenging due to the memory and compute resources needed to parse these files. With support from the Amazon Sustainability Data Initiative, our group is now creating and maintaining HRRR model output in an optimized format, Zarr, in a publicly-accessible S3 bucket- hrrrzarr. HRRR-Zarr contains sets for each model run of analysis and forecast files sectioned into 96 small chunks for every variable. The structure of the HRRR-Zarr files are designed to allow users the flexibility to access only the data they need through selecting subdomains and parameters of interest without the overhead that comes from accessing numerous GRIB2 files. , and History: This effort began in 2015 to illustrate the use of a private cloud object store developed by the Center for High Performance Computing (CHPC) at the University of Utah. We began archiving thousands of two-dimensional gridded fields (each one containing over 1.9 million values over the contiguous United States) from the High-Resolution Rapid Refresh (HRRR) data assimilation and forecast modeling system. The archive has been used for retrospective analyses of meteorological conditions during high-impact weather events, assessing the accuracy of the HRRR forecasts, and providing initial and boundary conditions for research simulations. The archive has been accessible interactively and through automated download procedures for researchers at other institutions that can be tailored by the user to extract individual two-dimensional grids from within the highly compressed files. Over a thousand users have voluntarily registered to use the HRRR archive at the University of Utah. Our archive has grown to over 130 Tbytes of model output but we no longer need to continue that effort since the GRIB2 files are available now via Google and AWS. As mentioned above, we now provide much of the same information in an alternative format that is appropriate particularly for machine-learning applications.
- Keyword:
- data assimilation, Zarr, weather, forecasts, high resolution rapid refresh, and numerical weather prediction
- Subject:
- atmospheric science
- Creator:
- Horel, John and Blaylock, Brian
- Contributor:
- University of Utah Center for High Performance Computing, NOAA Earth Systems Research Laboratory, Amazon Open Data Program, and NOAA Environmental Modeling Center
- Depositor:
- BRIAN MCBRIDE
- Owner:
- JOHN HOREL
- Based Near Label Tesim:
- Alaska, Alaska, United States and United States, , United States
- Language:
- binary and English
- Date Uploaded:
- 07/10/2019
- Date Modified:
- 04/18/2024
- Date Created:
- 2015-04-18 to 2019-07-10
- License:
- CC BY – Allows others to use and share your data, even commercially, with attribution.
- Resource Type:
- Dataset
- Identifier:
- https://dx.doi.org/10.7278/S5JQ0Z5B